The study protocol is publicly available here.

You should receive the local document pack after you have expressed interest in participating in HEAL-COVID. This will be sent to the proposed PI and the R&D contact, with other contacts (e.g. co-investigators, research nurses) copied in if we have been given contact details.

If your site have expressed interest but you do not have access to the local document pack, please email us at trial.team@heal-covid.net.

Any hospital in the UK that treats, or may treat, COVID-19 patients can take part in HEAL-COVID. We are keen to have as many NHS sites participating as possible.

Yes, we wish to be prepared for any potential future increase in COVID-19 admissions.

In order to give you the “Green Light” to open to recruitment we will need you to provide us with:

• A named PI for each site within the trust
• A Good Clinical Practice (GCP) certificate for the PI only
• Site staff to have completed self-directed online study training
• Signed Organisation Information Document (OID)

Signed Site Agreement (this is the model Non-Commercial Agreement and there is no scope for negotiation of terms)

Once we have confirmation that your hospital is very likely to take part in HEAL-COVID we will generate log-in details for your site. These will be sent to the proposed PI, who will change the password and share the log-in details with the team supporting the study so that they can complete the training and view the documentation.

Log-in details are provided per site, not for each individual. PIs are responsible for ensuring that these log-in details are shared only with those who will be working on HEAL-COVID.

No, all our training materials are shared on the study website, to be completed at your convenience. You will need to complete the training as is relevant to your role on the study (e.g. if you will be randomising patients you must complete the randomisation training, if you will be taking consent you must complete the consent training). The HEAL-COVID training covers the core principles of GCP, as relevant to the study.

We will not be conducting initiation visits, you will be initiated remotely once the minimum criteria have been met (“Green Light”).

HEAL-COVID patients can be co-enrolled with the following studies:

• RECOVERY
• REMAP-CAP
• PHOSP-C
• ISARIC CCP-UK

Co-enrolment with other interventional studies requires agreement from both study teams. If you have interventional studies running at your site that might be recruiting the same patient group and you wish to consider co-enrolment, please get in touch.

Yes, if you work across multiple hospitals within one trust you can work on HEAL-COVID at all of these, as long as the local PI at each site is aware. You will need to complete the training record at each site separately, and ensure that you use the correct site log-in details for the site you are working at.

At present we can only recruit patients to HEAL-COVID at the end of their inpatient admission (in the 5 days before they are expected to be discharged). We are exploring the possibility of recruiting patients who have been previously hospitalised later, in the community post-discharge. If this is safe and feasible for future arms of the study, the protocol will be amended and community care teams will be approached for involvement.

Please email us at trial.team@heal-covid.net and we will get back to you ASAP. You can also check the study Twitter feed for updates about study progress, @heal_covid.